SARS-CoV-2 Infection in Pregnant Japanese Women

Abstract

 On January 28, 2020, in response to the outbreak of multiple SARS-CoV-2 positive persons in Japan, the Ministry of Health, Labor and Welfare decided that it was a designated infectious disease. According to Article 23, Paragraph 6 of the Infectious Diseases Control Law Enforcement Regulations, pregnant women are positioned at high risk along with the elderly persons and patients with several complications and are subject to hospitalization measures. In studies of Japan Association of Obstetrician and Gynecologists, the frequency of SARS-CoV-2 positive pregnant women tended to be lower than that of the general population, and the main transmission route was domestic, and the number of positives tended to be higher in the third trimester. In the pregnant women who delivered during SARS-CoV-2 infection control, 24.1% had preterm birth and 84.3% had a caesarean section in the delivery mode. In multivariate linear regression analysis, the pregnant women aged 32 years and older, and 24 weeks of gestation and later were independent risk factors for severe SARS-CoV-2 infection. At this point, this emerging infectious disease continues unabated, and by the time the manuscript is published, it is possible that it will enter a new stage and the response of the government and medical practice will change. Therefore, in this paper, I will reproduce the various measures taken in the field of obstetrics and gynecology up to this point in chronological order, and keep them as records.