2022 Volume 58 Issue 1 Pages 31-36
Mother-to-child transmission of cytomegalovirus（CMV）is the most frequent TORCH syndrome, with 1％ –2％ of pregnant women developing primary CMV infection during pregnancy, resulting in a 30％ –50％ rate of fetal infection. However, a previous report has shown that educating pregnant women on prevention of CMV infection reduces their risk of primary infection. In the current study, the effectiveness of information provision for preventing primary CMV infection in pregnant women was verified. This study included 2,568 women who gave birth during a 4-year period in our hospital. Pregnant women without CMV infection were extracted by testing for the presence of CMV IgG antibodies during their first trimester. The women without CMV infection were made aware of preventative measures against CMV infection. CMV IgG antibodies were measured during the first trimester of 1,283 cases, of which, 380 cases（29.6％）were IgG-negative. Among them, two cases（0.5％） became positive for CMV IgG during the third trimester. The primary infection rate in pregnant women who were educated on infection prevention was lower than the previously reported rate of 1％–2％.
