Severe acute pancreatitis in a pregnant patient with coronavirus infectious disease（COVID-19）

Abstract

 The novel coronavirus infections（COVID-19）during pregnancy are more likely to get severity and are high risk for premature delivery. Although the causality is unclear, some cases of acute pancreatitis with COVID-19 are also reported. We herein report the case of severe acute pancreatitis after COVID-19 pneumonia in pregnancy women, who resulted in delivery by cesarean section at 31 weeks gestation. A 37-year-old nulligravida women was admitted to referral hospital at 29 weeks gestation for COVID-19 pneumonia. Nine days after the diagnosis of COVID-19, she experienced epigastric pain with elevated amylase level, and was diagnosed as severe acute pancreatitis. While being treated for pancreatitis, the labor started at 31 weeks gestation, where she was transported to our hospital and delivered by cesarean section for indication of low-lying placenta and COVID-19. She had no risk factors of acute pancreatitis: including alcohol and gall stones. Pregnant women with COVID-19 should be managed considering not only respiratory disease and obstetrics complication, but various complications including acute pancreatitis.