Two preterm cases of early congenital syphilis born from women with no prenatal care

Abstract

 Congenital syphilis has been increasingly reported in Japan, mirroring the rise in syphilis cases nationwide. Early diagnosis and treatment of syphilis in pregnant women are critical to preventing congenital syphilis. However, a lack of prenatal care in some cases results in unrecognized infections until the later stages of pregnancy, delaying appropriate treatment.

 This report presents two preterm cases of early congenital syphilis in neonates born to mothers who did not receive prenatal care. Despite challenges in diagnostic testing due to the critical condition of the infants, PCR successfully identified the pathogen. Antibacterial therapy, combined with supportive care, led to favorable short-term outcomes.

 These cases highlight the pressing need to raise public awareness of sexually transmitted infections and to strengthen support systems for women.