Revision of CBA Score Test Using Discriminative Analysis

Abstract

In neonatal jaundice, differentiation of biliary atresia from neonatal hepatitis is difficult. Several methods of differential diagnosis have been devised such as CBA score test and others. CBA score test has been made from history, physical findings and dada of chemical examinations. However, methods of chemical examination are different for each facility. Therefore, the data of chemical examination are needed to be revised in each facilities. This paper describes a trial to revise the CBA score test using discriminative analysis. Twentyeight cases of neonatal jaundice have been subjected to the study. As chemical examination for this discriminative analysis, direct bilirubin, GOT, GPT and alkaline phosphatase were used. The case with over 5 points on CBA score test has been decided to be biliary atresia. In our 14 cases which need not operation, 4 of 5 cases with over 5 points on original CBA score test have become under 5 points using this discriminative analysis. It seems that the misdiagnosis of neonatal hepatitis for biliary atresia decreased by using this analysis. This discriminative analysis is one of the evolution for CBA score test. It is important to make more useful score count with modifing CBA score in each facilities.