Abstract
Adrenocortical carcinoma is rare in children. In this paper, two pediatric patients of the adrenocortical carcinoma were presented. Both patients showed Cushing's syndrome and adrenogenital syndrome. The first case was a girl, age of 3, showing a moon face, precocious puberty, hypertension and hypokalemia. She had an adrenocortical carcinoma of the left adrenal gland, which was successfully resected. The clinical stage was III. She died of the recurrence seven months after the operation. The second case was a boy, age of 10, showing a moon face, precocious puberty and hypertension. He had a right adrenal tumor, which was unresectable because of the local invasion and the distant metastases. The clinical stage was IV. The histological examination revealed an adrenocortical carcinoma. He died of DIG nine days after the operation.
