Abstract
Thirteen cases of immature teratomas from the various sites were studied by immunohistochemistry using antihuman alpha-fetoprotein (AFP) antibody.Of those, four cases were preoperatively known to have abnormal serum AFP level. The AFP were definitely positive in the tubular epithelium of various types, i. e. flat and single, cuboidal, tall columnar with or without Goblet cells, and on the small islands of hepatoid cells, all of which were the endodermal elements. Other immature components such as neuro-ectodermal or mesenchymal tissues were all negative for AFP. Cases with positive results of AFP in the tissue were the same to the cases who showed the abnormality of serum AFP level.
