Abstract
We experienced a case of female infant with very low birth weight (1,009g), whose ileum was obstructed with tenacious meconium. Resection of stenosed ileum and tube ileostomy were performed. At the beginning, we could not rule out meconium ileus by trypsin activity test of meconium. Therefore we gave her N-acetyl cysteine. In 3 months we could rule out mucoviscidosis by clinical findings and sweat test. We finally diagnosed it as "meconium disease" named by Rickham, but it was also similar to "meconium plug syndrome" named by Clalworthy. In this paper we discussed about meconium disease in comparison with meconium ileus and meconium plug syndrome.
