A Case of Dysgerminoma With High Serum Concentration of Both HCG and α-Fetoprotein in a 12-Year-Old Girl

Abstract

Dysgerminoma is divided into two types, i.e., pure type and mixed type. Mixed type is associated with other various elements of germ cell tumors. We experienced a case of mixed type with high serum concentration of both human chorionic ganadotropin (=HCG) and α-Fetoprotein (=AFP). The patient is a 12-year-old girl who was admitted in Osaka University hospital because of abdominal distension and elevated serum HCG and a-Fetoprotein. Tumor was originated from right ovary. Histopathological diagnosis was Dysgerminama. The prognosis and the therapy of mixed type Dysgerminoma was discussed.