Intra-arterial Chemotherapy for Initially Unresectable Hepatoblastoma in Infant : A Case Report

Abstract

Intra-arterial administration of adriamycin in combination with cip-platinum and 5-fluoro-uracil dispersed in a lipid contrast medium(Lipiodol), "FAC-LIP.", was used in an infant with initially unresectable hepatoblastoma. "FAC-LIP" selectively remains in the tumor tissue more than 1 month, and a significant reduction in tumor size was noted. Subsequent resection is not performed because of the evidence of pulmonary metatasis. "FAC-LIP" was also useful to avoid the the toxicities of the anti-tumor drugs to the host.