The Changes in the Clinical Features of Hypertrophic Pyloric Stenosis : An analysis of 267 cases

Abstract

Two hundred and sixty seven infants with hypertrophic pyloric stenosis (HPS) were treated at our institution from January 1966 to December 1989. According to the year of admission, the four study groups, group (66-69), group (70-74), group (75-79) and group (80-89) were devided and reviewed on differences in sex, birth weight, birth order, body weight at admission, age at presentation of vomiting, serum electrolytes and blood gas analysis at admission. No significant differences are found in demographic characteristics. On the other hand, the mean values in group (75-79) for serum chloride (96.2 ± 8.0mEq/l), base excess (0.98 ± 5.0mEq/l) are significantly different between the group (66-69) and the group (70-74). The duration of vomiting becomes shorter year by year, and is associated with the changes of clinical features. This study makes it clear that the abnormalities for serum electrolytes and base excesses in the recent cases of HPS tend to reduce and these changes result from the shortening of the duration of vomiting.