1992 Volume 28 Issue 5 Pages 999-1008
Ninety-one children with perforated appendicitis treated surgically at the authors' hospital are reviewed. The organisms isolated from their peritoneal fluid at operation were 138 strains, such as Escherichia coli (37%), Bacteroides fragilis (23.2%), Pseudomonas aeruginosa (12.3%), Enterococcus species (7.2%) and et al. Though the antibiotics which was sensitive to Escherichia coli and Bacteroides fragilis and was not sensitive to Pseudomonas aeruginosa and Enterococcus species was chosen intra-and post-operatively, there were no postoperative complications such as wound infection and intraabdominal abscess. It is concluded that because there are little role in pathogenesity of Pseudomonas aeruginosa and Enterococcus species in perforated appendicitis, the antibiotics therapy for perforated appendicitis should be performed mainly for Escherichia coli and Bacteroides fragilis.
