A Case of Malignant Rhabdoid Tumor of the Kidney

Abstract

An 11-month-old girl with malignant rhabdoid tumor of the kidney underwent left nephrectomy with dissection of paraaortic lymph nodes followed by postoperative chemoradiotherapy. The patient did not respond to the treatment, and died of tumor 14 months later. At autopsy. metastase were found in the lungs, chest wall, diaphragm and liver. Lymph node metastase were also seen around the left bronchus, in mediastinum, at paracardiac region and at the head of pancreas. Immunohistochemical studies demonstrated that tumor cells stained positively for vimentin, α_1-antichymotrypsin and keratin. Only 3 survivors of such kidney tumors have been reported among 17 reported cases in Japan.