Abstract
This is case report of multicentric neuroblastoma, which is thought to maturate to ganglioneuroma with chemotherapy. 1 year 7 month old girl was admitted to our hospital due to mediastinal and retroperitoneal tumor. Labolatory data showed the elevation of serum LDH and urinary VMA, HVA level. CT scan showes mediastinal and retroperitoneal tumor, and bone scintigram showed positive uptake in both field. Chemotherapy was started in the diagnosis of multicentric neuroblastoma. During chemotherapy, CT showed no change of the size in both tumors, but LDH, VMA, HVA level were gradually decreased. Three years later, operation has done and pathological finding showed ganglioneuroma of both tumors.
