Abstract
A 5-year-old girl with a presacral neuroblastoma is reported. When she was 3 months old, she was first admitted with a chief complaint of a huge abdominal mass and subcutaneous nodules. Histology of the biopsied subcutaneous nodules revealed neuroblastoma, and surgery was undertaken after 8 courses of chemotherapy. The tumor originating from right adrenal gland was resected with her right kidney, combined with lymphonodes resection and intraoperative radiation. Then she was also given postoperative adjuvant chemothrapy, but the levels of u-VMA and u-HVA were not normalized. Her postoperative course was uneventful without reccurent or metastatic lesions appearing. At the age of 5, a presacral tumor was detected by a regular check-up of computed tomography, and was resected immediately, after which the levels of u-VMA and u-HVA decreased to normal range. Histology showed well differentiated ganglioneuroblastoma and no further therapy was required. The retrospective evaluation of computed tomography showed the presacral tumor on the first admission. Preopeartive chemotherapy reduced the size of tumor and the origin of the tumor was supposed to be right adrenal gland ; however a residual tumor was missed in her presacral space. We conclude this case might be ipsichronous multifocal neuroblastoma.
