Abstract
Gastrointestinal polyps are one of the complications of tuberous sclerosis (TS). However, most cases are asymptomatic. We report a very rare case of TS with anemia caused by bleeding from colon polyposis. The patient was a 3-year-old boy, who had been suffering from TS in another hospital since he was a neonate. He was referred to our hospital because of bloody stool when he was 2 years old. Countless polyps were observed from the sigmoid colon to the rectum. They were diagnosed as hyperplastic polyps by biopsy. We decided to observe him closely therafter. After observation for six months, the extent of the polyps remained the same and his anemia did not improved. We decided to remove the bowel with polyposis by the Soave pull-through method because it was difficult to improve his anemia by iron supplementation. A histological diagnosis indicated hamartomatous polyposis. TS is defined by a combination of small and large symptoms. Hamartomatous polyps are one of the small symptoms of TS. Most of the reported cases of TS with polyps were asymptomatic, and they rarely required any treatment. However, some cases require removal of the bowel with polyposis because of bloody stool or anemia.
