2017 Volume 53 Issue 6 Pages 1155-1160
Purpose: Prepubertal testicular tumors are rare and represent only 1 or 2% of all pediatric solid-type tumors. These tumors have different histologic characteristics, molecular biology features, and prognoses from those found in adults. We investigated the clinical features of pediatric testicular tumors in nine patients, who had been diagnosed and treated in our department.
Methods: We retrospectively reviewed the medical records of the nine patients with pediatric testicular tumors, who had been treated at the University of Tsukuba Hospital. We then analyzed the clinical features, treatments, and prognoses.
Results: There have been nine children, aged <15 years, who had been diagnosed with testicular tumors over the past 37 years. The pathological diagnoses of these tumors included 4 mature teratomas, 1 immature teratoma, 1 embryonal carcinoma, and 3 yolk sac tumors. All the patients were classified as Stage I, with no lymph node involvement. All the patients received radical orchiectomy, except for 1 patient with a mature teratoma. This patient received testicular sparing surgery. Only one patient with embryonal carcinoma received retroperitoneal lymph node dissection. None of these patients underwent chemotherapy. There were no recurrences within the average follow-up period of 5.2 years. All the patients have shown event-free survival.
Conclusions: The infant patients with Stage I testicular tumors received radical orchiectomy without any adjuvant therapy and showed a good prognosis. From our experience, radical inguinal orchiectomy without any postoperative chemotherapy is a good treatment choice for patients with Stage I testicular tumors.
