Pediatric Gastroduodenal Ulcer Following Acute Gastroenteritis or Influenza Infection

Abstract

Helicobacter pylori infection is known to be the major cause of gastroduodenal ulcer. We report seven cases of pediatric gastroduodenal ulcer secondary to infections other than Helicobacter pylori infection. The patients had a median age of 5 years (1–9 years), and four of the seven patients had underlying diseases. Three developed gastroduodenal ulcer following acute gastroenteritis including rotavirus and norovirus, and the other four developed them after suffering from influenza A infection. Two patients underwent laparoscopic surgery for duodenal ulcer perforation. Five patients were diagnosed as having gastroduodenal ulcer bleeding revealed by endoscopy and all required blood transfusions. Two of them underwent endoscopic hemostasis. In acute abdomen or gastrointestinal bleeding following acute gastroenteritis or influenza infection, the possibility of gastroduodenal ulcer should be kept in mind.