2023 Volume 59 Issue 2 Pages 198-202
We report the case of a 13-year-old boy who presented with ulcerative colitis (UC) and later developed cerebral venous sinus thrombosis (CVST). At the age of 10 years, he visited a hospital with a complaint of bloody stool and was diagnosed as having total colitis-type UC by colonoscopy. He was managed with mesalamine and prednisolone, but he had repeated remissions and relapses. Although remission of his UC was achieved with azathioprine therapy, he was admitted to our hospital for a relapse of abdominal pain and hematochezia. On the 8th day of admission, he complained of numbness and weakness in the left arm and leg. Brain Computed Tomography and Magnetic Resonance Imaging showed CVST. Immediate treatment with heparin for venous sinus thrombosis and mannitol to reduce cerebral edema was started. However, owing to treatment resistance, thrombectomy was performed by endovascular therapy six days after onset. After the thrombectomy, his convulsion symptoms resolved, and his paralytic symptoms were alleviated. The patient’s headache resolved, and he was discharged from the hospital 50 days after onset. CVST is rarely reported in pediatric patients with UC, and we report this case with a review of the literature from Japan.