Management Strategies for Pediatric Moderately Differentiated Sertoli–Leydig Cell Tumor of the Ovary

Abstract

An 11-year-old girl was admitted to our hospital because of abdominal distention and abdominal pain. Abdominal contrast-enhanced computed tomography (CT) revealed a pelvic mass and a large amount of ascites. Contrast-enhanced magnetic resonance imaging (MRI) revealed a ruptured right ovarian tumor, but its benign or malignant nature remained uncertain. Intraoperatively, a 10 cm ruptured tumor was identified in the right ovary. We preserved the ovarian capsule and selectively resected the tumor. Histopathological examination confirmed the diagnosis of a moderately differentiated Sertoli–Leydig cell tumor. The patient underwent a two-stage procedure, namely, right adnexal resection with partial omentectomy and staging laparotomy. Despite the high-risk nature of the tumor, the patient did not wish to undergo postoperative chemotherapy. Two years after surgery, no recurrence has been detected. The clinical course and treatment of Sertoli–Leydig cell carcinoma in children remain largely unknown. Treatment decisions should be made through careful consultation with the patient and their family, with vigilant postoperative monitoring.