2025 Volume 61 Issue 4 Pages 755-761
Only a few detailed reports exist on the treatment course for large sacral yolk sac tumors (YST) with metastases. In this report, we present the case of a young girl with sacral YST and multiple metastases who achieved remission through a multidisciplinary approach without significant complications. The patient was a 1-year-and-7-month-old girl diagnosed with a large sacral YST (Altman type III) with metastases to the lymph nodes, lungs, and liver. Preoperative BEP chemotherapy successfully reduced the tumor size, allowing for surgical intervention. Abdominal exploration and lymph node biopsy were conducted laparoscopically, and the tumor was excised from the buttocks to the tailbone. No significant postoperative complications were observed. Postoperative chemotherapy eliminated the pulmonary metastases, while the liver metastases showed residual shadows but no signs of activity. The patient was discharged on postoperative day 109. At approximately 11 months after completing treatment, there was no evidence of recurrence. This case underscores the importance of combining effective chemotherapy with tailored surgical strategies to achieve complete tumor resection, a key prognostic factor in the management of large sacral YSTs.
