Abstract
It has not been understood how the bronchial lesion develops in cases of sinobronchial syndrome (SBS). In the present study, pulmonary function and airway hyperresponsiveness (AHR) were examined in 30 cases of chronic sinusitis (CS) and 40 cases of SBS to determine the factors influencing the development of bronchial diseases. In cases of CS, routine pulmonary function tests were all within normal and about 10% of cases revealed peripheral airway obstruction which was correlated with the AHR. In cases of SBS, FEV_<1.0>% was reduced in 60% of cases. Peripheral airway obstruction tended to precede the reduction of FEV_<1.0>% and the severity of obstructive change may be related to AHR.
