Abstract
A 67 year old Japanese male visited to orthpedic clinic because of prostatic carcinoma metastatic to the lumbar spine. A routine Chest X-ray showed multiple calcificatied lesion in the bilateral middle and lower lung lobes, Then, the patient was transferred to our clinic. Bronchofiberscopy revealed the presence of several, (a number of) elevated, yellow nodules in the tracheobronchial trees. Histologically, the nodule were found to be deposits of eosinophilic amorphous material in the submucosa, which stained pink with congo red. Since the material kept affinity for Congo-red after the treatment of KMnO_4, we regarded the material as amyloid of AL protein, Further examinations showed no Bence Jonce protein in the urine and no myeloma cells in the bone mallow. No clinical evidence of amyloid deposits was found in the other organs So, we diagnosed the patient as a primary amyloidosis extensively involving the tracheobronchial trees and lung.
