Abstract
A 52-year-old asymptomatic man who had abnormal shadows on chest roentogenogram was admitted. Chest X-ray showed mass-like opacities in the right hilum and in the lower left lung field. Chest CT scan showed a mass-like opacity with an air bronchogram in the right middle lobe and a wedge-shaped shadow adjacent to the pleura in the lingular segment. Bronchoscopic findings showed mucosal flare, swelling, and stenosis of right B^6. BALF revealed increasing of IgG, lymphocyte fraction, and CD19 and CD20 positive cells. Cytological diagnosis was class IIIa. Specimens obtained by transbronchial biopsy(TBB) resulted in lymphoma, diffuse small cell type, IgG λ type. Gene rearrangement analysis of the specimens presented a rearranged band of the heavy chain. Gene rearrangement analysis of specimens obtained by TBB may be useful in the diagnosis of primary pulmonary lymphoma.
