Abstract
It is difficult to diagnose primary pulmonary lymphoma preoperatively and discriminate from other lymphoproliferative diseases. We reported 2 cases of resected primary pulmonary MALT type lymphoma. The first case was diagnosed as MALT type lymphoma based on the preoperative diagnosis by immunohistological examination of TBLB specimen. The other case was also strongly suspected to be a MALT type lymphoma preoperatively based on bronchial brushing cytology, flow cytometric analysis of BALF and elevation of serum γ-globulin level. When this disease is suspected, diagnose can be performed by flow cytometric analysis of BALF and immunohistological examination of TBLB specimens. In addition to these techniques, it is essential to prove rearrangement of immunoglobulin genes and T cell receptor genes for definitive diagnosis.
