Abstract
The purpose of this study was to clarify the clinical usefulness of Perfluoroctyl Bromide (PFB), developed by Long et al in 1972, as a contrast medium for bronchography as well as alveolography. Compaired to Dionosil, bronchography by PFB emulsion showed slightly less effect in terms of contrast per se, but great advantage was seen in terms of shortening the time necessary for bronchiolar absorption of PFB emulsion. On the other hand alveolography by pure PFB showed the following advantages ; 1. Alveoli in question can be depicted by postural change. 2. Quantitative evaluation of the intrapulmonary distribution of destroyed alveoli is possible. 3. Excretion in expired gas by vaporization in a short period of time. 4. In experiment animals no pathological changes were seen 1 month after alveolography. 5. No clinically significant side effects. In conclusion Perfluoroctyl Bromide showed clinically more usefulness for alveolography than bronchography.
