The Journal of the Japan Society for Respiratory Endoscopy
Online ISSN : 2186-0149
Print ISSN : 0287-2137
ISSN-L : 0287-2137
A Case of Pulmonary Sarcoidosis with Endobronchial Involvement and Bilateral Pleural Effusion
Keisuke KojimaKousuke KashiwabaraHajime IwagoeDaisuke NotsuteJunji HamamotoKazuhiko FujiiHirotsugu Kohrogi
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2009 Volume 31 Issue 6 Pages 386-391

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Abstract
Background. We report a case of pulmonary sarcoidosis with endobronchial involvement and bilateral pleural effusion. Case. A 27-year-old man was admitted because of dry cough and shortness of breath. Chest radiography and computed tomography (CT) revealed bilateral mediastinal and hilar lymphadenopathy and bilateral pleural effusion. The pleural effusion revealed lymphocyte-predominant exudate. Bronchoscopy showed bronchial mucosal irregularity and small nodules. The bronchoalveolar lavage fluid revealed an increase in the number of lymphocytes and the CD4/CD8 ratio. Transbronchial lung biopsy and bronchial biopsy showed non-caseating epithelioid cell granuloma. These findings are compatible with sarcoidosis. Corticosteroid therapy immediately improved the symptoms, pleural effusion and bronchoscopic findings. Conclusion. This is a rare case of pulmonary sarcoidosis with endobronchial involvement and bilateral pleural effusion.
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© 2009 The Japan Society for Respiratory Endoscopy
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