2017 Volume 39 Issue 1 Pages 28-33
Background. Pulmonary giant cell carcinoma is rare, and it is considered to be very difficult to definitively diagnose by bronchofiberscopy. Case. We herein report the case of a 77-year-old man with granulocyte colony stimulating factor (G-CSF)-producing giant cell carcinoma of the lung who had initially been diagnosed with a lung abscess. He was admitted to our hospital due to the presence of a mass shadow on the left lower lobe of the lung that increased in size on a chest X-ray, despite the administration of broad-spectrum antibiotics. A presumptive diagnosis of a lung abscess was made, and his antibiotic therapy was continued. However, the symptoms and inflammatory reaction persisted. Thus, flexible fiberoptic bronchoscopy was performed. Bronchoscopy revealed a polypoid tumor in the left B10b bronchus. Lung biopsy showed giant cell carcinoma that was positive for G-CSF and the patient's serum G-CSF level was elevated. As a result, this patient was diagnosed with G-CSF-producing giant cell carcinoma of the lung. Conclusion. This is a rare case of pulmonary giant cell carcinoma that was diagnosed by bronchofiberscopy.
