2024 Volume 46 Issue 1 Pages 31-35
Background. Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) is a malignant lymphoma in which mature B cells proliferate in a monoclonal fashion and infiltrate into the peripheral blood, lymph nodes, and spleen. It is a rare disease in Japan, accounting for 2-3% of all leukemias, and there have been no reports from Japan of CLL/SLL diagnosed using endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). In addition, securing a sufficient amount of tissue is necessary for making a definitive diagnosis by EBUS-TBNA. Case. A 76-year-old man visited our hospital complaining of cough, bloody sputum, and dyspnea. Airway constriction sounds were heard with a stethoscope, and a mass shadow with a maximum diameter of 75 mm in the mediastinum was found on chest CT. EBUS-TBNA puncture was performed five times via bronchoscopy, and CLL/SLL was diagnosed via a histopathological examination. Conclusion. We herein report a case of CLL/SLL diagnosed using EBUS-TBNA. It is necessary to consider the possibility of malignant lymphoma, including CLL/SLL, when airway constriction sounds are auscultated.
