Transbronchofiberscopic Intracavitary Infusion Treatment of Pulmonary Aspergilloma

Abstract

The asperglloma cavity of a 67 year-old female was infused with amphotericin B via the bronchofiberscope. Six doses of 25mg amphotericin B and one dose of 35mg all in 10ml of 5% glucose solution, were administered at weekly intervals. The aspergilloma disappeared and thickening of the cavity wall regressed on chest X-ray films. Fungi were not observed in sputum after treatment. There were few side effects. In inoperable cases, this method of aspergilloma treatment is thought to be effective and safe.