Tracheobronchopathia Osteochondroplastica A Report of Two Cases

Abstract

Two cases of tracheobronchopathia osteochondroplastica were reported. Case 1 was a 54-year-old woman who had complained of dry cough and hoarseness. Her chest X-ray film showed irregularity in the tracheal wall and narrowing of the tracheal lumen. Her flow volume loop suggested a typical pattern of upper airway obstruction. A fiberoptic bronchoscopic examination revealed multiple irregular nodular lesions in the trachea and the main bronchi. The biopsy specimen of the nodular lesion disclosed submucosal bony tissue covered with normal bronchial epithelium. Case 2 was also a 54-year-old woman who consulted an otolaryngologist because of productive cough and hoarseness. In a fiberoptic examination of the larynx, multiple small nodular lesions were serendipitously found in the trachea. Her chest X-ray film was essentially normal. Bronchofiberscopy revealed multiple firm nodular lesions on the tracheal cartilages. Diagnosis was confirmed by the histopathologic study of the biopsy specimen.