Abstract
We have investigated the platelet volume of normal adults and a few cases of several diseases. Coulter Counter ZBI was used in measuring the platelet volume. The results are as follows:
1) About the investigation of normal adults, the platelet volume in females and old persons showed a slight increase.
2) In the advanced stage of ITP, both the mode and the mean platelet volume showed the decrease, while in the recovered stage of ITP, normalization was shown.
3) In chronic active hepatitis and liver cirrhosis, the platelet volume was generally large, and showed the decrease after bleeding.
4) In DM and IHD, the platelet volume showed a slight increase. From the above results we are of the opinion that the measurement of the platelet volume gives a great help in understanding the platelet function. On the other hand the change of the platelet volume is closely related to haemorrhagic diathesis.