Abstract
In an attempt to evaluate the clinical significance of “Hepaplastintest”, comparative studies have been undertaken by simultaneous observation on Hepaplastintest, Owren's Thrombotest and Quick's one step prothrombintest respectively.
159 cases with liver diseases, including acute, chronic hepatitis, cirrohsis of the liver, hepatoma and fatty liver.
Significantly lower hepaplastintest values were obtained in acute stage of acute hepatitis, chronic hepatitis active form and cirrohsis as compared with other types of liver diseases.
Earlier recovery of hepaplastintest value as within two weeks was impressed in acute hepatitis, contrasting to definite delay of recovery in subacute hepatitis as long as more than one month.
In chronic hepatitis active form with sublobular zonal necrosis, concomitant lower values both in choline esterase arid hepaplastintest were impressive.
In cirrohsis, preceeding depression of hepaplastintest value was noted shortly before the onset of hepatic failure.