1978 Volume 9 Issue 2 Pages 229-232
Changes in coagulation-fibrinolysis system were observed during anethesia and gynecologic operations (67 cases) with different kinds of fluid therapy (each 500ml of low molecular weight dextran, hydroxyethyl strach, gelatin and Hartman's solution, plus additional Hartman's solution or blood, in cases).
Hypercoagulability characterized by shortening of partial thromboplastin time, elevated fibrinolytic activity characterized by decrease in plasminogen and increase in FDP were observed. Decreases in platelet count and fibrinogen were also observed.
These changes seemed to be non-specific reaction during anesthesia and operations, and were independent on the fluids infused under the condition.
