1978 Volume 9 Issue 2 Pages 248-251
Intracranial hemorrhage has been the lethal complication in hemophilia and is also the most common cause of death in hemophiliacs in Japan. So, we studied retrospectively on intracranial hemorrhage for 127 patients with hemophilia (hemophilia B, 18) referred to Kanagawa Children's Medical Center. Reported are 6 month old boy with hemophilia A and 5 month old boy with hemophilia B, who had neurosurgical treatment for intracranial hemorrhage. The case with hemophilia B is the first reported case treated with neurosurgery in Japan.
The results of retrospective studies are follows: Incidence; 23/127 (18.1%), Traumatic history; 8/23 (34.8%), Bleeding sites; unknown 16, subarachnoid hemorrhage 5, and subdural hematoma 2, Relapse of symptoms; 6/23 (26%) and Prognosis; antiepileptic drugs 9/23 (39%), mental deterioration 2 and cerebral palsy 1. Motality rate of surgical treatment for intracranial hemorrhage was high in hemophiliacs because of inadequate replacement therapy.
But, long term adequate replacement therapy has now became possible. So, neurosurgical ireatment can be more safely performed in hemophiliacs when adequate replacement therapy is maintained. We think that neurosurg tcal treatment should be indicated for intracr anial hematoma in hemophiliacs as well as the cases without bleeding tendency.
