Blood & Vessel
Online ISSN : 1884-2372
Print ISSN : 0386-9717
Prophylaxis and therapy of postoperative vein thrombosis
Takeshi UEYAMAMasaki TOMIKAWAKimitaka KAWAKITAYoshiharu KOMORI
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JOURNAL FREE ACCESS

1978 Volume 9 Issue 4 Pages 557-561

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Abstract
Prevention of postoperative vein thrombosis was accomplished by means of either low amount of heparin administration or physical treatments.
Heparin treatment groups
Group I: 160 cases of hysterectomy received total amount of 30, 000 IU heparin during 50hrs. postoperatively as shown in table 1.
Group II: 38 cases of vascular surgery were injected 5, 000 IU heparin 2hrs. prior to surgery, and postoperatively the same amount of heparin were administered as in group I.
Physical treatment group
Group III: 220 cases of hysterectomy were treated postoperatively by such physical therapies as raising up her legs, active and passive excercise and massage.
Results
Group I: 6 out of 160 cases showed hemorrhagic tendency and another 3 cases showed vein thrombosis.
Group II: This group showed no vein thrombosis, however a hematoma formation was encountered in 2 cases and postoperative bleeding on the suture line was in 1 case.
Group III: Vein thrombosis was appeared in 4 cases.
Conclusion
The administration of a low amount of heparin during both pre and postoperative phase (Group II) is effective enough to prevent the occurrence postoperative vein thrombosis. The effectiveness of the different two methods (Group I, III) in prophylaxis of the vein thrombosis is not so enough as in Group II.
Pain or sudden swelling on the legs during the physical treatment are very useful informations to detect a venous thrombosis in the early postoperative phase.
Immediately after a venous thrombosis is detected, heparin and urokinase therapy should be initiated. This kind of anticoagulant therapy can prevent the pulmonary embolism and postphlebitic syndrome.
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© The Japanese Society on Thrombosis and Hemostasis
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