Abstract
One autopsy case of a 69-year-old male with severe hemophilia A was reported, who died of a massive cerebellar hematoma. Normal follicles of lymphnodes and spleen were destructed and mesenteric lymphnodes were infiltrated by non-Hodgikin's lymphoma cells. Moreover multiple lesions of Aspergillus were also found. Since one year before his death, the number of CD4 lymphocytes had been below 200/mm3 and the levels of IgG and IgM had increased. Although he had remained as an asymptomatic carrier of HIV infection (CDC group II), he had some symptoms of AIDS from the pathological point of view. These findings indicated that anti-viral, anti-fungal and immunological therapies should be started before the decline of cellular immunity in the patients with HIV infection.
