INFLUENCE OF 2-HOUR INTERRUPTION OF AGITATION ON IN VITRO PROPERTIES OF VOLUME-REDUCED PLATELETS WASHED WITH M-SOL IN SYRINGE

Abstract

Volume-reduced washed platelets (VR-wPLTs) are useful not only for avoiding circulatory overload, but also for reducing adverse reactions. On investigating VR-wPLTs infusion by syringe, the influence of a 2-hour interruption of agitation on the in vitro properties of VR-wPLTs (44.1 ml, 2.13×10¹¹ PLTs) in M-sol in the syringe was investigated. After 2-hour storage on a bench at room temperature, the pH was maintained above 6.8, and MPV, %disc, CD62P, annexin V, %HSR, and aggregation values were not significantly changed. These results indicate that a 2-hour interruption of agitation negligibly affected the in vitro properties of VR-wPLTs in the syringe.