2019 Volume 65 Issue 5 Pages 817-822
The Japanese Red Cross Society prepares Irradiated Frozen-Thawed Red Cells from two different sources: Red Blood Cells and Irradiated Red Blood Cells. The procedures used for preparation from the two sources differ by whether X-ray irradiation is performed before or after freezing and thawing. X-ray irradiation is widely known to exert some adverse effects on erythrocytes. Therefore, if the two preparative procedures result in differences in hemoglobin recovery, it would be advisable to choose the superior of the two procedures. We compared the quality of Irradiated Frozen-Thawed Red Cells prepared using the two different preparative procedures. We found no significant differences in hemoglobin recovery or hemolysis between the procedures. The potassium concentration in the supernatant was slightly different between the irradiation timings, but the difference exerts little adverse effect on blood transfusion samples.
