2021 Volume 67 Issue 3 Pages 449-454
Analysis of heart rate variability was performed by continuous monitoring of pulse rate in prolonged vasovagal reactions (VVR) occurring during platelet apheresis.
Before the onset of VVR, regular fluctuation of ΔNNI (0 ms, 8-10 ms, 15-19 ms) and a stable pulse rate were observed. Immediately before the onset of VVR, a sharp decrease in pulse rate was observed, followed by disappearance of regularity in ΔNNI. The onset of VVR was clinically recognized at the same time as the increase in pNN50.
In the early stage of recovery, the frequency of pulsation with ΔNNI of 0 ms was increased, and regular fluctuations followed. However the peak of ΔNNI observed in the histogram appeared to be expanded position. When the donor moved to the treatment room, an increase of pNN50 was observed and the pulse rate again decreased. The clinical symptoms then worsened. It is likely that the activation of vagal activity during the recovery process lead to delayed recovery.
Continuous pulse rate monitoring is thought to be useful for understanding the recovery process of blood donors. Monitoring is expected to allow a rational determination of the end of prolonged VVR.