2024 Volume 70 Issue 1 Pages 33-38
A 69-year-old woman treated for Evans syndrome underwent direct antiglobulin test (DAT) -positive autologous blood transfusion perioperatively during hip replacement surgery. Hemolytic findings of the stored erythrocyte products did not differ over time from those of the components of erythrocyte products supplied by the Japanese Red Cross Society. DAT intensity of the first stored autologous erythrocytes remained unchanged for 35 days, while dissociated fluid antibody titer decreased 16-fold up to Day 21 and 8-fold after Day 28. The DAT intensity of autologous erythrocytes in the second blood reservoir remained unchanged for 14 days, and the antibody titer of the dissociated fluid showed a 4-fold decrease. Clinical course following administration of 4 units of DAT-positive autologous red blood cells and 2 units of autologous fresh-frozen plasma up to 48 hours postoperatively was satisfactory, without evidence of hemolysis. Few studies have reported the effectiveness of stored autologous blood transfusion in DAT-positive patients, and many points are unclear. Here, we experienced a case in which an effective transfusion effect was obtained by performing appropriate preliminary evaluation and product monitoring.
