Primary Jejunal Histiocytic Sarcoma with Spontaneous Perforation in a Dog

Abstract

An 8-year-old spayed female Jack Russell Terrier presented with acute bacterial peritonitis. Laparotomy revealed two jejunal perforation sites, both of which were surgically resected. Histopathology and immunohistochemistry revealed that both lesions were histiocytic sarcomas. The dog recovered uneventfully, and received seven treatments of intravenous carboplatin. There were no recurrences of visible tumors or perforative peritonitis until the dog died at postoperative day 185 due to chronic diarrhea of unknown causes. This is the first report of canine primary jejunal histiocytic sarcoma; the present case suggests that spontaneous perforation may occur even in small lesions for which surgical resection is useful.