The Tohoku Journal Veterinary Clinics
Online ISSN : 1883-4590
Print ISSN : 0916-7579
ISSN-L : 0916-7579
A Fundamental Study of Causal Factors of Uric Acid Urolithiasis in Newborn Piglets
Jun Kakino
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1998 Volume 21 Issue 2 Pages 50-60

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Abstract
In newborn piglets, the primary aim of this study is to focus on the relationship between the incidence of uric acid urolithiasis and starvation or low body weight. 1) The results indicated that the outbreak of the disease was not an unusual thing, and that starvation, low body weight and reduced ambient temperature were related to an occurrence of the disease. 2) The results suggested that the occurrence of the disease was related to a hypofunction of liver and kidney, lactic acidosis and increased catabolism of protein accompanying starvation. 3) The results suggested that the occurrence of uric acid urolithiasis in the newborn piglets was attributable to increased purine catabolites due to a starvational condition after birth. 4) The results suggested that increased concentrations and excretions of uric acid in the urine were due to starvation, and a decrease of levels of urinary pH were due to an increase of lactic acid concentrations in the urine. On the basis of the above findings, it is suspected that uric acid urolithiasis in newborn piglets occur because of increased purine catabolism due to starvation.
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© Japanese Society of Veterinary Clinics
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