An Outbreak of Fatal Bordetella bronchiseptica Pneumonia in Japanese Macaques （Macaca fuscata）

Abstract

　Four Japanese macaques（Macaca fuscata） showed respiratory symptom, and died. Gross examination showed severe diffuse pneumonia. Histological examination showed fibrinopurulent bronchial pneumonia with Gram negative short bacilli in all cases. Immunohistochemically, the short bacilli observed in 3 of 4 cases were strongly positive for Bordetella bronchiseptica（Bb）. Bb was isolated from the lung lesion. The present cases were diagnosed as an outbreak of fatal Bb pneumonia. The present case is the first report of fatal Bb pneumonia in Japanese macaques.