Calcinosis Circumscripta in a Malayan Box Turtle (Cuora amboinensis kamaroma)

Abstract

A case of calcinosis circumscripta in the limbs of a Malay box turtle(Cuora amboinensis kamaroma) was examined. At death, the turtle showed severe enlargement of the fore and hind limbs. There were multifocal nodules with a chalky appearance and gritty consistency in the subcutis and muscle layers of the limbs. Histologically, the nodules contained multiple lobular lesions of various sizes and shapes, surrounded by varying amounts of fibrous connective tissue. The lesions consisted of various amounts of amorphous basophilic material that were positive for PAS and von Kossa's reaction. The morphological features of the lesions closely resembled those of calcinosis circumscripta in dogs and humans.