1960 Volume 12 Issue 4 Pages 629-635
Recently, long acting sulfonamides plus INH has been recommended for pulmonary tuberculosis therapy.
This Study comprised 32 cases of serious pulmonary tuberculosis. Patients were treated daily with 1 gm. of IHMS and 0.5 gm. of sulfadimetoxine for 6 months. The results were as follows:
1) Body temperature, body weight, blood-sedimentation rate, cough, sputum and appetite were slightly improved by this chemotherapy.
2) We did not fine remarkaple change of tubercle bacille.
3) The breast roentgenogram showed improvement of 24% about infiltration and of 15% about cavity.
4) Blood picture:
a) Anemia recovered in 6 months.
b) In the cases with leucocyte count below 5,000 and neutrophil count below 3,000, the former rose to above 5,000 and the latter to above 3,000 in 6 months. The leucocyte count or the neutrophil count did not fall.
5) The abnormalities in the liver function tests recovered in 6 months.
6) Side action found very little and lesser compared with sulfisomidin: INH therapy.
