1962 Volume 14 Issue 3-4 Pages 846-851
In this text it is discussed that sympathomimetic effects of ephedrine may be elicited through the metabolic alteration of intracellular catecholamines.
In cytoplasma, ephedrine is demethylated to norephedrine, possible active substance which may be liberator of noradrenaline from granules. Ephedrine tachyphylaxis may be related to the lecreased production of norephedrin and the adrenaline-receptor block by ephedrine.