An Autopsy Case of Monocytic Leukemia Treated with Steroid Hormone and Anticancer Drug

Abstract

Department of Pathology, Kansai Medical School A 39 years old houswife was diagnosed as having monocytic leukemia. Clinical symptoms and the peripheral blood picture were improved by administration of steroid hormone combined with anticancer drugs (6-Mercapto-Purine, and Mitomycin C), but the bone marrow showed no improvement. The patient died 6 months after the onset of symptoms. Among the necropsy findings were ulceration of the stomach and massive atrophy of the adrenals, perphaps, due to prolonged treatment with steroid hormone and infiltration with leukemic cells.