1967 Volume 19 Issue 1 Pages 14-39
Since there seems to be a close relationship between thyroid gland and cold stress, this paper deals with the histological changes occurring in the thyroid gland of tumor-bearing rats during and after hypothermia.
As a result, we could demonstrate that the function of the thyroid gland increased during lowered body temperature, but was depressed during rewarming.
These findings suggest that such alteration of the host through cooling and rewarming provides a favourable soil to metastases.