Experimental Studies on Eye Wall Resection Operation in Rabbit Eye

Abstract

The purpose of present experiments was to investigate feasibility of Sclero-Uveoretinectomy for an resection of intraocular tumor, intraocular biopsy and extraction of nonmagnetic intraocular foreign bodiy.
Presen t experiments were performed in two different procedure. One is a so-called trephine method and the other a scleral flap method.
A trephine method was performed to investigate an area and limitation for Sclero-Uveoretinectomy.
A surgical procedure of the trephine method was as follows:
Three week prior to resection, a rabbit eye was treated by diathermy, photocoagulation or cryotherapy. After a chorioretinal scar was developed, a scleral supporting ring was sutured in the episclera and eye wall resected by trephine 8mm in diameter. A resected area was transplantated with a scleral homograft.
A surgical procedure of a scleral flap method was as follows:
After a scleral supporting ring was sutured, a scleral flap w as made, diathermy was appplied in around an area to be resected. under a sclaral flap After diathermy was applied, sclero-chorioretinectom y was performed and the scleral flap was sutured.
A procedure for biopsy of the choroid and the retina was as follows.
A scleral supporting ring was sutured and a scleral flap (7×7mm) was made in equator region. After scleral flap was formed, diathermy and wet-field coagulation or cryotherapy was made in an area to be resected under a sclaral flap and partial screo-chorioretinectomy was performed beneath the scleral flap. The scleral flap was sutured.
The result were as follow:
1. Eye balls tolerated aga i nst these kinds of operations.
2. Complications which occurred in eye wall resection were bleeding from choroidal vessels, vitreous loss, vitreous hemorrhage, postoperative inflammation, retinal detachment, infection and phthisis bulbi.
3. Diathe rmy coagulation was effective to prevent bleeding from the choroidal vessels during entire procedure and postoperative complication.
4. Eyes which were resected 180°in the anterior segment developed in phthisis bulbi.
5. Eyes resected an horizontal meridian of the globe including the long posterior c iliary artery met severe vitreous hemorrhage and showed an inevitable poor prognosis.
6. Eyes resected in a vertical meridian of the globe excluding the long posterior ciliar artery met a few complications and took a good prognosis.
7. Biopsy specimen could, be removed by application of diathermy and cryotherapy without destruction of histological structure, but structure of biopsy specimen which was removed by wet-field coagulation was greatly destroyed. Comparing these kinds of proce dures, we could demonstrated a posibility of partial eye wall resection or biopsy of the retino-chroidal tissue. A scleral flap method using a scleral supporting ring was made with a few complications. Application of diathermy and cryotherapy under a scleral flap were necessary to prevent from choroidal bleeding.